Studying apolipoprotein turnover with stable isotope tracers: correct analysis is by modeling enrichments
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منابع مشابه
Studying apolipoprotein turnover with stable isotope tracers: correct analysis is by modeling enrichments.
Lipoprotein kinetic parameters are determined from mass spectrometry data after administering mass isotopes of amino acids, which label proteins endogenously. The standard procedure is to model the isotopic content of the labeled precursor amino acid and of proteins of interest as tracer-to-tracee ratio (TTR). It is shown here that even though the administered tracer alters amino acid mass and ...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2006
ISSN: 0022-2275
DOI: 10.1194/jlr.m600302-jlr200